Computational Methods for Predicting Protein‐Protein Interactions Using Various Protein Features
نویسندگان
چکیده
منابع مشابه
Computational methods for predicting protein-protein interactions.
Protein-protein interactions (PPIs) play a critical role in many cellular functions. A number of experimental techniques have been applied to discover PPIs; however, these techniques are expensive in terms of time, money, and expertise. There are also large discrepancies between the PPI data collected by the same or different techniques in the same organism. We therefore turn to computational t...
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Motivation: Proteins play a fundamental role in every process within the cell. Understanding how proteins interact, and the functional units they are part of, is important to furthering our knowledge of the entire biological process. There has been a growing amount of work, both experimetal and computational, on determining the protein-protein interaction network. Recently researchers have had ...
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Protein-protein interactions play a crucial role in the cellular process. In recent years, yet new experimental techniques have been developed to discover the protein-protein interaction networks, the accuracy and coverage has still proven to be limited. Computational approaches come into being essential both to assist in the design and validation of experimental studies and for the prediction ...
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ژورنال
عنوان ژورنال: Current Protocols in Protein Science
سال: 2018
ISSN: 1934-3655,1934-3663
DOI: 10.1002/cpps.62